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Understanding the mechanistic links between nutrition and non-communicable diseases in LMICs (MRC/GCRF call)

Escrito por NOP (aip)  em 9 de Janeiro de 2019

The MRC GCRF call on understanding the mechanistic links between nutrition and non-communicable diseases (NCDs) in low and middle-income countries (LMICs) is part of the MRC’s suite of strategic activities in global health and nutrition research.

The overarching aim of this call will be to address mechanistic evidence gaps between nutrition/diet and susceptibility and prevalence of NCDs in a context-specific manner.

Research questions should be context-specific and build on or enhance existing epidemiological data or observations – to strengthen mechanistic understanding of the relationship between nutrition and NCDs. The outcomes will be expected to pave the way for future context-specific interventions or provide concrete evidence enabling further research into the upstream determinants of nutrition and diet-related risk factors.

The funding call will be phased to have an outline stage and a full application stage. There will be a developmental phase, whereby successful outlines will receive funds to further develop and strengthen their proposal and the required collaborations, ahead of submission for the more substantive call.


Medical Research Council (MRC)

Prazo de inscrição

quinta-feira, 04 de Abril de 2019 às 13:59 (9 dias restantes)

Critérios de elegibilidade

We welcome industrial collaborators but note that they cannot be recipients of funding. The role of industrial partners must be clearly explained, with special emphasis on the benefit to LMICs. A letter of support from the industrial partner must be included in the development stage proposals.

The lead applicant must be based at a UK higher education institution or at an eligible independent research institution (including all MRC units and institutes) and all funding is to be managed through that organisation. Researchers based in institutions in LMICs are eligible to apply as co-Is or collaborators only and not as the lead applicant. LMIC co-Is may be based at higher education institutions, non-profit research institutions or non-governmental organisations.

Research teams will be expected to forge partnerships between relevant disciplines as well as researchers, non-governmental organisations, and the private sector in LMICs, as appropriate. Bringing in expertise and researchers not traditionally associated with nutrition research is particularly encouraged.

There must be clear evidence of equitable partnerships with, and scientific leadership from, co-Is based in the countries where the project will take place. Proposals should take into account how capacity building for junior UK and developing country staff will lead to developing future scientific leadership, particularly within LMICs. Plans should be put in place to ensure continued partnership and development beyond the duration of the proposed work.

To enable equitable partnerships, as well as to optimise research plans and ensure that these are informed by the specific needs of the participating LMIC(s), the developmental stage applications should already include the key partners. It is expected that LMIC-based researchers are co-Is at the development phase, but additional partners (co-Is or collaborators) can be included at the full application stage (see Application process for details).

Applications should articulate a clear and specific case for the relevance of the proposed research to the LMIC partners and provide evidence that the proposed plan of research is informed by the needs of LMIC partners.

The funding call will be phased to have a development stage and a full application stage.

At the development stage, applications must: (i) lay out the research questions, justify their context-specificity and primary relevance to the affected populations, propose experimental approaches and provide an indicative resource request for the full bid; (ii) detail the partnership building and bid-development activities that will take place at the development stage. Guidance for development stage applications is provided on this page.

Successful applications will receive development stage awards (up to £50,000 MRC contribution, for up to 10 months). These funds would cover the period from the beginning of the development award until the expected start date of the full stage award. So, for successful applicants, the full stage award can follow through the developmental stage. This funding will enable teams to better develop their research questions, strengthen the contributions from each of the partners, or engage new partners, map and/or collate existing preliminary evidence and data sources (see eligible costs). We expect that teams and research plans will continue to be developed between the outline and full stages, and that supported proposals will need to maintain research flexibility, to refine plans in response to emergent findings. Development stage awards will need to start in July 2019.

Applications for the development stage must follow the guidance provided and be submitted via the Joint electronic-submission (Je-S).

The closing date for development stage applications is 4 April 2019.


Global Challenges Research Fund (GCRF)


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