The present study aimed to evaluate the association between syphilis in pregnancy and low birth weight, small for gestational age, and preterm birth.
A total of 17 930 817 live births were included in the study. Of these, 155 214 (8.7/1000) were exposed to syphilis during pregnancy. Maternal syphilis increased the odds of low birth weight (aOR 1.88, 95% CI: 1.85–1.91), small for gestational age (aOR 1.53, 95% CI: 1.51–1.56), and preterm birth (aOR 1.35, 95% CI: 1.33–1.37). Higher odds were observed for pregnant women with VDRL titer ≥64 and untreated maternal syphilis when compared to mothers without syphilis. Analysis stratified by prenatal care showed higher odds for all adverse birth outcomes for mothers attending ≤6 prenatal appointments.
Autoria: Helena Benes Matos da Silva, Rita de Cássia Ribeiro Silva, Elzo Júnior, Mauricio Barreto, Enny Paixão, Maria Yury Ichihara.
Periódico: International Journal of Gynecology and Obstetrics
Ano de publicação: 2024