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Follow up of a robust meta-signature to identify Zika virus infection in Aedes aegypti: another brick in the wall

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Abstract

The mosquito Aedes aegypti is the main vector of several arthropod-borne diseases that have global impacts. In a previous meta-analysis, our group identified a vector gene set containing 110 genes strongly associated with infections of dengue, West Nile and yellow fever viruses. Of these 110 genes, four genes allowed a highly accurate classification of infected status. More recently, a new study of Ae. aegypti infected with Zika virus (ZIKV) was published, providing new data to investigate whether this “infection” gene set is also altered during a ZIKV infection.

Autoria: Artur Queiroz, Pablo Ivan Ramos.

Periódico: Memória do Instituto Oswaldo Cruz

Ano de publicação: 2018

DOI: https://doi.org/10.1590/0074-02760180053

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